Answer
Darunavir inhibits HIV-1 protease dimerisation and catalytic activity, selectively blocking cleavage of HIV-encoded Gag-Pol polyproteins in virus-infected cells and thereby preventing formation of mature infectious virus particles.
Sources for this answer
- Darunavir 800 mg Film-coated TabletsViatris (formerly Mylan or Upjohn) · emc · SmPC §5.1 Pharmacodynamic properties · Version 8Document updated
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