Answer
Darunavir in Symtuza inhibits HIV-1 protease dimerisation and catalytic activity, selectively blocking cleavage of HIV-encoded Gag-Pol polyproteins in infected cells and thereby preventing formation of mature infectious virus particles.
Sources for this answer
- Symtuza 800 mg/150 mg/200 mg/10 mg film coated tabletsJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.1 Pharmacodynamic properties · Version 17Document updated
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