Answer
Darunavir ethanolate inhibits HIV-1 protease dimerisation and catalytic activity, selectively blocking cleavage of HIV-encoded Gag-Pol polyproteins in virus-infected cells and thereby preventing formation of mature infectious virus particles.
Sources for this answer
- PREZISTA 100 mg/ml oral suspensionJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.1 Pharmacodynamic properties · Version 21Document updated
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