Answer
Colistimethate sodium is a prodrug of colistin, a polymyxin antibiotic that binds to and changes bacterial cell membrane permeability, causing bacterial death, with bactericidal activity against Gram-negative bacteria possessing a hydrophobic outer membrane.
Sources for this answer
- Promixin 1 million International Units (IU) Powder for Nebuliser SolutionZambon UK Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 15Document updated
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