Clopidogrel · Medicine question

How does clopidogrel affect repaglinide exposure?

iatroX medicinesPublished 8 November 2026

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Clopidogrel increases repaglinide exposure in healthy volunteers through CYP2C8 inhibition by its glucuronide metabolite, as shown in vitro; concomitant administration requires caution because plasma concentrations may increase.

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Plavix 300mg tabletsSANOFI · emc · SmPC §4.5 Interaction with other medicinal products · Version 25Document updated 22 January 2025

Sources checked 8 November 2026

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