Answer
In patients with Parkinson's disease taking immediate-release ropinirole 2 mg three times daily, ciprofloxacin increased ropinirole Cmax by 60% and AUC by 84%, potentially increasing adverse events and requiring ropinirole dose adjustment when ciprofloxacin is introduced or withdrawn.
Sources for this answer
- Requip XL prolonged-release tabletsGlaxoSmithKline UK · emc · SmPC §4.5 Interaction with other medicinal products · Version 26Document updated
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