Answer
Cimetidine may compete with metformin, a component of Competact, for renal tubular transport; in seven healthy volunteers, cimetidine 400 mg twice daily increased metformin exposure (AUC) by 50% and peak concentration (Cmax) by 81%.
Sources for this answer
- Competact 15 mg/850 mg film coated tabletsNeon Healthcare Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated
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