Answer
Cenobamate increases phenytoin blood concentrations, so phenytoin concentrations should be monitored during cenobamate titration and the phenytoin dose may need reduction based on individual response.
Sources for this answer
- Ontozry 200 mg film-coated tabletsAngelini Pharma UK-I Limited (Formerly Arvelle Therapeutics UK) · emc · SmPC §4.5 Interaction with other medicinal products · Version 8Document updated
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