Answer
Benzydamine hydrochloride reduces inflammation mainly by inhibiting synthesis of proinflammatory cytokines, including TNF-α and IL-1β; it weakly inhibits prostaglandin synthesis, while membrane stabilisation and inhibition of the neutrophil oxidative burst are further proposed mechanisms.
Sources for this answer
- Benzydamine 0.15% w/v MouthwashADVANZ Pharma · emc · SmPC §5.1 Pharmacodynamic properties · Version 9Document updated
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