belatacept · Medicine question

How does belatacept inhibit T-cell activation?

iatroX medicinesPublished 8 November 2026

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Belatacept binds to CD80 and CD86 on antigen-presenting cells, blocking CD28-mediated co-stimulation of T cells and thereby inhibiting their activation.

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NULOJIX 250 mg powder for concentrate for solution for infusionBristol Myers Squibb Pharmaceuticals limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 18Document updated 8 September 2026

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