Answer
Belantamab mafodotin enhances recruitment and activation of immune effector cells, which kill tumour cells through antibody-dependent cellular cytotoxicity and phagocytosis; the apoptosis it induces also produces markers of immunogenic cell death, which may contribute to an adaptive immune response to tumour cells.
Sources for this answer
- Blenrep 100mg & 70 mg powder for concentrate for solution for infusionGlaxoSmithKline UK · emc · SmPC §5.1 Pharmacodynamic properties · Version 2Document updated
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