atosiban acetate · Medicine question

How does atosiban acetate reduce uterine contractions?

iatroX medicinesPublished 8 November 2026

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Atosiban acetate competitively blocks human oxytocin receptors, antagonising uterine contractions and inducing uterine relaxation in human pre-term labour.

Sources for this answer

Tractocile 7.5 mg/ml Solution for InjectionFerring Pharmaceuticals Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 13Document updated 29 July 2026

Sources checked 8 November 2026

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What monitoring of uterine contractions and fetal heart rate should be considered during atosiban acetate treatment?Does atosiban acetate cross the placenta?Has the safety and efficacy of Tractocile (atosiban acetate) been established in pregnant women under 18?Have clinically relevant interactions been found between atosiban acetate and labetalol or betamethasone?What precaution applies to atosiban acetate in patients with impaired liver function?

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