Answer
Atgam’s exact immunosuppressive mechanism is unknown, but published data suggest it primarily depletes circulating lymphocytes, especially T lymphocytes, and may also make T lymphocytes unresponsive through antibody binding.
Sources for this answer
- Atgam 50 mg/ml concentrate for solution for infusionPfizer Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 3Document updated
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