Answer
Aflibercept acts as a soluble decoy receptor, binding VEGF-A and PlGF with higher affinity than their natural receptors and thereby inhibiting their binding to and activation of VEGF receptors.
Sources for this answer
- Eylea 40mg/ml solution for injection in a vialBayer plc · emc · SmPC §5.1 Pharmacodynamic properties · Version 23Document updated
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