adalimumab · Medicine question

How does adalimumab neutralise the biological activity of TNF?

iatroX medicinesPublished 8 November 2026

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Answer

Adalimumab binds specifically to TNF and neutralises its biological activity by blocking its interaction with the p55 and p75 cell surface TNF receptors.

Sources for this answer

Humira 40 mg solution for injection in pre-filled pen (Great Britain)AbbVie Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 24Document updated 16 February 2026

Sources checked 8 November 2026

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