acenocoumarol · Medicine question

How does acenocoumarol prevent blood clotting?

iatroX medicinesPublished 8 November 2026

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Answer

Acenocoumarol blocks vitamin K-epoxide-reductase, reducing vitamin K-dependent gamma-carboxylation of clotting factors II, VII, IX and X, a process needed for their interaction with calcium and initiation of blood clotting.

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Sinthrome Tablets 1 mgNorgine Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 6Document updated 25 July 2025

Sources checked 8 November 2026

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