Answer
In ciprofloxacin/dexamethasone ear drops, ciprofloxacin kills bacteria by inhibiting DNA gyrase and topoisomerase IV, while dexamethasone reduces inflammation through corticosteroid receptor-mediated increases in anti-inflammatory proteins and suppression of inflammatory genes, although its mechanism is not fully understood.
Sources for this answer
- Ciprofloxacin/Dexamethasone 3mg/ml + 1mg/ml ear drops, suspensionAspire Pharma Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 2Document updated
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