How do the three active ingredients in Trixeo Aerosphere work in the airways?

In Trixeo Aerosphere, budesonide reduces airway inflammation, glycopyrronium blocks muscarinic M3 receptors on airway smooth muscle to widen the airways, and formoterol activates beta-2 adrenergic receptors to produce rapid, long-lasting relaxation of bronchial smooth muscle in patients with reversible airways obstruction.