Answer
The active metabolites of emtricitabine + tenofovir disoproxil fumarate, emtricitabine triphosphate and tenofovir diphosphate, competitively inhibit HIV-1 reverse transcriptase, resulting in DNA chain termination.
Sources for this answer
- Truvada film-coated tabletsGilead Sciences Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 43Document updated
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