Answer
In Omidria, phenylephrine contracts the iris radial muscle to dilate the pupil, while ketorolac inhibits COX1 and COX2, reducing prostaglandins to lessen postoperative pain and inflammation and potentially prevent surgically induced pupil constriction.
Sources for this answer
- Omidria 10 mg/mL + 3 mg/mL concentrate for solution for intraocular irrigationRayner Pharmaceuticals Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 3Document updated
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