Answer
In Actikerall, fluorouracil inhibits DNA and RNA synthesis, inhibiting cell growth, while salicylic acid reduces hyperkeratosis through a keratolytic effect thought to involve disrupting adhesion between corneocytes and promoting their loosening and detachment.
Sources for this answer
- Actikerall 5mg/g + 100mg/g Cutaneous SolutionAlmirall Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 7Document updated
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