Answer
Conjugated oestrogens in Premarin replace oestrogen lost after menopause, relieving menopausal symptoms by binding to nuclear receptors in oestrogen-responsive tissues, and reduce elevated luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels through negative feedback.
Sources for this answer
- Premarin 0.3 mg Coated TabletsPfizer Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 30Document updated
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