Answer
In Exblifep, cefepime kills bacteria by binding penicillin-binding proteins and inhibiting cell-wall synthesis, while enmetazobactam inhibits class A extended-spectrum beta-lactamases, protecting cefepime from hydrolysis.
Sources for this answer
- EXBLIFEP 2 g/0.5 g powder for concentrate for solution for infusionADVANZ Pharma · emc · SmPC §5.1 Pharmacodynamic properties · Version 1Document updated
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