Answer
Toremifene taken on the day of surgery may, through its relatively high binding affinity and potentially high plasma concentrations, displace rocuronium or vecuronium from complexes with Bridion (sugammadex sodium), delaying recovery of the T₄/T₁ ratio to 0.9.
Sources for this answer
- Bridion 100 mg/ml solution for injectionMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 25Document updated
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