testosterone · Medicine question

How can testosterone affect oral anticoagulants?

iatroX medicinesPublished 8 November 2026

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Testosterone can increase oral anticoagulant effects by modifying hepatic coagulation-factor synthesis and competitively inhibiting plasma protein binding, so close monitoring of prothrombin time and INR is recommended, especially when testosterone is started or stopped.

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Testogel 16.2mg/g gelBesins Healthcare (UK) Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 6Document updated 27 January 2025

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