Answer
St John's wort may increase the metabolism of the oestrogens and progestagens in Kliofem, potentially reducing its effect and changing uterine bleeding patterns.
Sources for this answer
- Kliofem 2 mg/1 mg film-coated tabletsNovo Nordisk Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 22Document updated
Sources checked