How can ritonavir or cobicistat interact with Maxitrol eye drops?

Ritonavir or cobicistat may reduce dexamethasone clearance from Maxitrol eye drops, increasing its effects and risking adrenal suppression/Cushing's syndrome; avoid the combination unless benefits outweigh the increased risk of systemic corticosteroid side-effects, and monitor for systemic corticosteroid effects if used.