How can ritonavir or cobicistat interact with Maxidex (dexamethasone)?

Ritonavir or cobicistat may decrease dexamethasone clearance from Maxidex, increasing its effects and risking adrenal suppression/Cushing's syndrome; avoid the combination unless benefits outweigh the increased risk of systemic corticosteroid side effects, in which case monitor for systemic corticosteroid effects.