Answer
Rifampicin, a strong CYP3A4 inducer, may increase clindamycin hydrochloride clearance and reduce its effectiveness, so monitoring for loss of effectiveness is advised.
Sources for this answer
- Dalacin C 75mg Capsules / Clindamycin 75 mg CapsulesPfizer Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 21Document updated
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