Answer
Sildenafil taken within the preceding 24 hours may significantly intensify the blood-pressure-lowering effect of sodium nitroprusside dihydrate, so use requires strict risk–benefit consideration and particularly careful dose titration.
Sources for this answer
- Sodium Nitroprusside 50 mg/2 mL Concentrate For Solution For InfusionAFT Pharma UK Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 1Document updated
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