disopyramide · Medicine question

How can phenytoin affect blood levels of disopyramide and its metabolite?

Name: How can phenytoin affect blood levels of disopyramide and its metabolite?
Published: 2026-11-08T01:45:29.380Z

iatroX medicinesPublished 8 November 2026

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Phenytoin, a CYP3A inducer, may lower disopyramide blood levels and increase levels of its metabolite MN-disopyramide; this combination is not recommended because the magnitude of these effects is unpredictable.

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Rythmodan Retard 250mg Modified Release TabletsNeon Healthcare Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 2Document updated 10 December 2024

Sources checked 8 November 2026

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