Answer
Phenoxymethylpenicillin can reduce methotrexate excretion when taken with methotrexate, increasing the risk of toxicity.
Sources for this answer
- Phenoxymethylpenicillin Sugar Free 250mg / 5ml Powder for Oral SolutionBrown & Burk UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 3Document updated
Sources checked