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Medicines busulfanQuestion & answer

busulfan · Medicine question

How can paracetamol affect busulfan clearance?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Paracetamol decreases glutathione levels in blood and tissues and may therefore decrease busulfan clearance when used in combination.

Sources for this answer

Busulfan 2 mg tabletsAspen · emc · SmPC §4.5 Interaction with other medicinal products · Version 10Document updated 16 July 2025

Sources checked 8 November 2026

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busulfan

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