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Medicines ondansetronQuestion & answer

ondansetron · Medicine question

How can ondansetron affect the pain-relieving effect of tramadol?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Data from small studies indicate that ondansetron may reduce the pain-relieving effect of tramadol.

Sources for this answer

SETOFILM 4 mg Orodispersible FilmsNorgine Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 7Document updated 3 June 2025

Sources checked 8 November 2026

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ondansetron

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