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Medicines daptomycinQuestion & answer

daptomycin · Medicine question

How can NSAIDs affect daptomycin levels?

iatroX medicinesPublished 8 November 2026

The answer

Answer

NSAIDs can increase daptomycin plasma levels by reducing renal filtration, which is the primary route of daptomycin clearance.

Sources for this answer

Cubicin powder for concentrate for solution for injection or infusionMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 26Document updated 19 November 2021

Sources checked 8 November 2026

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daptomycin

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