Answer
Grapefruit or grapefruit juice can increase capivasertib (Truqap) concentrations through strong CYP3A4 inhibition, potentially increasing toxicity, and the Truqap dose should be reduced when co-administered.
Sources for this answer
- Truqap 160 mg film-coated tabletsAstraZeneca UK Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated
Sources checked