Answer
Enrylaze (recombinant crisantaspase), when administered concurrently with or immediately before vincristine, may increase vincristine toxicity because asparaginase inhibits its hepatic clearance, although no interaction studies have been performed.
Sources for this answer
- Enrylaze 10 mg/0.5 ml Solution for injection/infusionJazz Pharmaceuticals UK Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 2Document updated
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