How can dapagliflozin affect lithium blood levels?

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Dapagliflozin may increase renal lithium excretion and decrease blood lithium levels, so lithium concentrations should be monitored more frequently after dapagliflozin initiation and dose changes, with referral to the lithium-prescribing doctor for monitoring.

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Forxiga 5 mg film coated tabletsAstraZeneca UK Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 30Document updated 24 September 2024

Sources checked 8 November 2026

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