Answer
Co-Diovan may reversibly increase serum lithium levels and toxicity, potentially further increasing toxicity because thiazides reduce lithium clearance; concomitant use is not recommended, and careful serum lithium monitoring is recommended if the combination is necessary.
Sources for this answer
- Co-Diovan 80/12.5 mg, 160/12.5 mg, 160/25 mg TabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 28Document updated
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