Answer
Ceftriaxone may increase the effect of vitamin K antagonist oral anticoagulants and bleeding risk, so INR should be monitored frequently and the anticoagulant dose adjusted accordingly during and after ceftriaxone treatment.
Sources for this answer
- Ceftriaxone powder for solution for injection 2gReig Jofre UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 3Document updated
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