calcium folinate hydrate · Medicine question

How can calcium folinate hydrate affect the efficacy of cotrimoxazole?

Name: How can calcium folinate hydrate affect the efficacy of cotrimoxazole?
Published: 2026-11-08T01:39:58.375Z

iatroX medicinesPublished 8 November 2026

The answer

Answer

Calcium folinate hydrate given with cotrimoxazole may reduce or completely neutralise cotrimoxazole's efficacy.

Calcium Folinate 10 mg/ml InjectionHospira UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 18Document updated 6 July 2026

Sources checked 8 November 2026

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