Answer
Amphotericin B may act synergistically with flucytosine, but concurrent use may increase flucytosine toxicity by possibly increasing its cellular uptake and/or impairing its renal excretion, requiring an individual patient benefit–risk assessment.
Sources for this answer
- Amphotericin B Gilead liposomal 50 mg Powder for dispersion for infusionGilead Sciences Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 28Document updated
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