Answer
Amlodipine may increase tacrolimus blood levels when co-administered, through a mechanism not fully understood, requiring monitoring of tacrolimus levels and adjustment of its dose when appropriate to avoid toxicity.
Sources for this answer
- Istin 5 mg TabletsViatris (formerly Mylan or Upjohn) · emc · SmPC §4.5 Interaction with other medicinal products · Version 29Document updated
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