Answer
Alecensa (alectinib hydrochloride) may increase plasma digoxin concentrations because alectinib and its major active metabolite M4 inhibit P-gp in vitro; appropriate monitoring is recommended when they are used together.
Sources for this answer
- Alecensa 150 mg Hard CapsulesRoche Products Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 17Document updated
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