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Medicines propofolQuestion & answer

propofol · Medicine question

Have abuse and dependence been reported with propofol?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Abuse of and dependence on propofol 1% have been reported, predominantly among healthcare professionals.

Sources for this answer

Propofol 10mg/ml (1%) emulsion for injection or infusionAspen · emc · SmPC §4.4 Special warnings and precautions for use · Version 29Document updated 3 November 2025

Sources checked 8 November 2026

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propofol

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Can propofol cause a slow heart rate or asystole?Can propofol cause low blood pressure and temporary pauses in breathing during induction of anaesthesia?How do alcohol and narcotic analgesics interact with propofol?What training is required for healthcare professionals administering propofol 1%?Why is propofol not recommended in newborn infants?How soon after preparation must the Aspen propofol 1% emulsion product diluted with 5% dextrose be used?

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