Answer
Prolonged use can reduce bone mineral density. Bone health and individual osteoporosis risks should be reviewed during continued use.
Sources for this answer
- Depo-Provera 150mg/ml Injection — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.