Answer
Omeprazole did not cause clinically relevant changes in osimertinib exposure in a clinical pharmacokinetic study and can be used concomitantly with Tagrisso (osimertinib mesylate) without restrictions.
Sources for this answer
- Tagrisso 40 mg film-coated tabletsAstraZeneca UK Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 32Document updated
Sources checked