Answer
Yes. Nitisinone can increase their exposure by inhibiting CYP2C9, so closer monitoring and prescriber-led adjustment may be needed.
Sources for this answer
- Orfadin 4mg/ml Oral Suspension — Current selected SmPCemc · Summary of Product Characteristics
- Nitisinone 10 mg hard capsules — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.