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Medicines nitisinoneQuestion & answer

nitisinone · Medicine question

Does nitisinone interact with warfarin or phenytoin?

iatroX medicinesPublished 21 August 2026Reviewed 21 August 2026

The answer

Answer

Yes. Nitisinone can increase their exposure by inhibiting CYP2C9, so closer monitoring and prescriber-led adjustment may be needed.

Sources for this answer

Orfadin 4mg/ml Oral Suspensionemc · SmPC Current selected SmPC · Version 10
Nitisinone 10 mg hard capsulesemc · SmPC Current selected SmPC · Version 3

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nitisinone

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