Answer
Its clearance is mainly linked to neutrophils rather than kidney function, and pharmacokinetic studies found no material effect from renal impairment. Treatment remains under specialist supervision.
Sources for this answer
- Pelmeg 6 mg solution for injection in pre-filled syringeemc · SmPC Current selected SmPC · Version 8
- NEULASTA Pre-Filled Syringeemc · SmPC Current selected SmPC · Version 5