Answer
Yes. Its blood-glucose-lowering effect declines as kidney function worsens, although its heart-failure and kidney-disease roles are not based solely on glucose lowering.
Sources for this answer
- Jardiance 10 mg and 25 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.